Publications
For a full list of my publications, see Google Scholar
Preprints
A designed Zn2+ sensor domain transmits binding information to transmembrane histidine kinases
A. Katherine Hatstat, Rian Kormos, Vee Xu, William F. DeGrado. bioRxiv, 2024. DOI: 10.1101/2024.10.30.621206
Peer-reviewed publications and review articles
Synthesis and analysis of novel catecholic ligands as inhibitors of catechol-O-methyltransferase
A. Katherine Hatstat, Grace Kennedy, C. Skyler Cochrane, Larryn W. Peterson, Mauricio Cafiero. Bioorganic and Medicinal Chemistry Letters, 2023, 88, 129286. DOI: 10.1016/j.bmcl.2023.129286
Small Molecule Improvement of Trafficking Defects in Models of Neurodegeneration
A. Katherine Hatstat, Michael D. Pupi, Michaela C. Reinhart, and Dewey G. McCafferty, ACS Chemical Neuroscience, 2021. DOI: https://doi.org/10.1021/acschemneuro.1c00524
Chemoproteomic-enabled characterization of small GTPase Rab1a as a target of an N-arylbenzimidazole ligand's rescue of Parkinson's-associated cell toxicity
A. Katherine Hatstat, Baiyi Quan, Morgan Bailey, Michael C. Fitzgerald, Michaela C. Reinhart, Dewey G. McCafferty, RSC Chemical Biology, 2022, Advance Article. DOI: https://doi.org/10.1039/D1CB00103E
Predicting PY motif-mediated protein-protein interactions in the Nedd4 family of ubiquitin ligases
A. Katherine Hatstat, Michael D. Pupi, and Dewey G. McCafferty, PLoS ONE, 2021. DOI: https://doi.org/10.1371/journal.pone.0258315
Synthesis and analysis of novel catecholic ligands as inhibitors of catechol-O-methyltransferase.
A. Katherine Hatstat, Grace Kennedy, C. Skyler Cochrane, Larryn W. Peterson, Mauricio Cafiero, in preparation.
Characterization of small-molecule induced changes in Parkinson’s-related trafficking and transport via the Nedd4 signaling pathway
A. Katherine Hatstat, Hannah D. Ahrendt, Matthew W. Foster, Leland Mayne, M. Arthur Moseley, S. Walter Englander, Dewey G. McCafferty, Cell Chemical Biology, 2021. DOI: 10.1016/j.chembiol.2020.10.008
BioRxiv pre-print: https://doi.org/10.1101/2020.06.01.128348
Robust and facile purification of full-length ubiquitin ligase human Nedd4 from Escherichia coli
A. Katherine Hatstat, Dewey G. McCafferty. Protein Expression and Purification, 2020. DOI: 10.1016/j.pep.2020.105649
Ab initio study of electronic interaction energies and desolvation energies for dopaminergic ligands in the catechol-O-methyltransferase active site
A. Katherine Hatstat, Mallory Morris, Larryn Peterson, and M. Cafiero. Computational and Theoretical Chemistry, 2016. DOI: 10.1016/j.comptc.2016.01.003.
MP2//DFT Calculations of Interaction Energies Between Acetaminophen and Acetaminophen Analogues and the Aryl Sulfotransferase Active Site
K.M. DiGiovanni, A. Katherine Hatstat, Jennifer Rote and M. Cafiero. Computational and Theoretical Chemistry, 2013. DOI: 10.1016/j.comptc.2016.01.003. DOI: 10.1016/j.comptc.2012.12.004
SELECTED ORAL PRESENTATIONS
2024: University of Pennsylvania Future Leaders in Biochemistry and Biophysics, Philadelphia, PA
2023: Gibbs Society Annual Conference on Biothermodynamics, Makanda, IL
2023: Leading Edge Symposium, HHMI Janelia Research Campus, Alexandria, VA
2020: #ChemistsLive, ACS Cross-Division Virtual Event
2020: St. Jude National Graduate Student Symposum, Memphis, TN (cancelled due to COVID-19)
2019: Southeast Regional Meeting of the American Chemical Society, Savannah, GA
2019
Chemistry Research Symposium, Duke University, Durham, NC
2016
Chemistry Departmental Seminar, Rhodes College, Memphis, TN
2016
Undergraduate Research Conference, University of Memphis, Memphis, TN